Hexes

Hexes are powerful indestructible items, obtained via Valeen, the Crone after defeating Seer, World's Heart. Hexes are completely optional. They exist solely to provide additional challenges for those seeking a greater difficulty.

There are a total of 8 hexes. However, Siegfried's Torment must be unlocked by completing a run in Othermine with Siegfried's Aegis.